Frontal fibrosing alopecia. Authoritative facts about the skin from DermNet New Zealand. Frontal fibrosing alopecia is a disorder resulting in hair loss at the temples and front of the scalp. Learn about the causes and treatment of FFA. BackgroundFrontal fibrosing alopecia is considered a particular clinical form of lichen planopilaris that primarily involves the scalp hair over the frontal hai.
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Summary and related texts. What you should be alert for in the history Women with frontal fromtal alopecia FFA note a rapid onset of frontal hair recession.
Expected results of diagnostic studies Skin biopsy is the main diagnostic test, but is not always necessary because of the distinct clinical features. FFA may be combined with more widespread oral or cutaneous lichen planus; this may alter treatment, if progressive symptomatic disease is present.
Results of a previous scalp biopsy had shown lymphocytic and granulomatous perifolliculitis with eccentric atrophy of follicular epithelia and fibroing fibrosis, confirming the diagnosis of FFA Figure 2 A. The prevalence of this association is not known; however, because 4 patients with generalized FFA were seen in our hair clinic within a relatively short period, we believe it is underdiagnosed.
Biopsies from the pale areas devoid of hair show only fibrous tracts and not the primary pathology. She had noticed no decrease in her eyelashes or eyebrows, but her facial skin had changed during the past 5 years Figure 1 C.
British Association of Dermatologists – Patient Information Leaflets (PILs)
Which of the following best describes your experience with hand-foot-and-mouth disease? Genetichormonal and environmental factors may be involved. This happens due to inflammation and destruction of the hair follicles. Sign in to access your subscriptions Sign in to your personal account. This may help frontal fibrosing alopecia become inactive in some people.
Frontal fibrosing alopecia
How to get funding? Unfortunately, their success is variable and some people cannot find a treatment that is effective for fibrpsing. The finding of gross interfollicular scarring, panfollicular lymphocytic inflammation, or involvement of the interfollicular epidermis in a biopsy should prompt a search for an alternate form of scarring alopecia that may mimic FFA. Whether current therapy ultimately alters the course or severity of FFA has not been established.
Frontal Fibrosing Alopecia
The incidence is reported to be increasing in white-skinned women, and it is uncommon in women with dark skin. Facial Papules in Frontal Fibrosing Alopecia: A skin biopsy may be performed to confirm the diagnosis. In some cases, there are skin coloured or yellowish follicular papules located on the forehead and temples .
Additional information Further information on this disease Classification s 1 Gene s 0 Other website s 0. Donati, Valente, fivrosing Romiti.
Frontal fibrosing alopecia FFA is a rare variant of lichen planopilaris see alopecai term characterized by symmetrical, progressive, band-like anterior hair loss of the scalp. In conclusion, the concept of FFA as a generalized disease is important for treatment planning and research. There are treatments that help to slow down or halt further hair loss in some people.
The areas of fibrosing alopecia do not appear grossly scarred and there is an absence of mottled pigmentation, marked scaling, pustules, or groups of hairs forming tufts. Types of research When to do research? Elderly women, often years after menopause, represent the main group who present with FFA.
Contact allergy or photocontact allergy to cosmetics, hair dye, and sunscreens have been suggested as possible causative factors .
Finasteride, at a dose of 2. Evidence of Vellus Follicle Involvement. Frontal fibrosing alopecia FFA is considered a particular clinical form of lichen planopilaris LPP that primarily involves the scalp hair over the frontal hairline. How is frontal fibrosing alopecia diagnosed? The newly affected hair follicles are surrounded by a lichenoid pattern of inflammation associated with scarring.
Etiology It was suggested that the disease could have a hormonal origin, but to date the precise etiology remains unknown. Sign in to customize your interests Sign in to your personal account. Potent steroid gels, lotions or creams applied to the skin on the front of the scalp can be helpful.
Further studies are needed to determine the prevalence of this involvement in patients with frontal fibrosing alopecia. At the margins of the bald areas, close inspection or dermatoscopy shows redness and scaling around hair follicles. Analysis and interpretation of data: A cross sectional observational case-control study.
For details of source materials used please contact the Clinical Standards Unit clinicalstandards bad. C, Recession of hairline and papules on the right lateral face of patient 2.
Treatment can be discontinued if the process has stabilized, but relapses may occur.
How do you choose a research theme? J Am Acad Dermatol ; Create a free personal account to download free article PDFs, sign up for alerts, customize your interests, and more. A year-old postmenopausal woman presented with frontal hairline recession that had started 3 months before her visit to the clinic; peripilar inflammation had developed in the same region.
What can I do? Histologic samples showed lichen planopilaris features involving the facial vellus.
Frontal Fibrosing Alopecia
Results of histologic testing. Negative results of DIF testing were observed in all specimens. An ointment or cream that acts by suppressing the immune system and calming the inflammation where it is applied. Some individuals with alopecia will prefer to wear a wig.